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Acquisition of self-reactive effector CD4 + T cells is a major component of the autoimmune response that can occur during myocarditis, an inflammatory form of cardiomyopathy. Although the processes by which self-reactive T cells gain effector function have received considerable attention, how these T cells contribute to effector organ inflammation and damage is less clear.
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Compensatory growth of organs after loss of their mass and/or function is controlled by hepatocyte growth factor (HGF), but the underlying regulatory mechanisms remain elusive.
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1993-10-5 · Among patients with various lung diseases, HGF revealed the Kd value to be 58 PM and the number of binding levels were 4.10 ng/ml in one with silicosis, 2.84 ndml in one sites was 1530 sitedpg of plasmamembranesproteinin with lung abscess, and in seven with pneumonia the level was the normal lung, whereas 1050 sitedpg of plasma membrane 1.06-2 ...
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RBC-1 encodes the 5"portion including the fourth kringle domain of a-chain, the entire p-chain of HGF, and a part of 3''-noncoding region. Hybridization was performed at 42 "C for 20 h …
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2005-4-1 · Hepatocyte growth factor (HGF), a member of growth factors, was originally identified in the serum of rats after partial hepatectomy. 1 It is a heterodimeric protein built of chain α with a molecular weight of 69 kDa and chain β with a molecular weight of 34 kDa. 2 HGF has been postulated to serve as an endogenous cardioprotective factor. 3 It protects cardiac myocytes …
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